中文名稱: 兔抗ABCC2多克隆抗體
英文名稱: Anti-ABCC2 rabbit polyclonal antibody
別 名: DJS; MRP2; cMRP; ABC30; CMOAT
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human
相關(guān)類別: 一抗
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. |
Applications: |
ELISA, IHC |
Name of antibody: |
ABCC2 |
Immunogen: |
Synthetic peptide of humanABCC2 |
Full name: |
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
Synonyms: |
DJS; MRP2; cMRP; ABC30; CMOAT |
SwissProt: |
Q92887 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
30-150 |