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  • 兔抗KIAA0556多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW10622
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱(chēng): 兔抗KIAA0556多克隆抗體

英文名稱(chēng): Anti-KIAA0556 rabbit polyclonal antibody

別     名: KIAA0556; JBTS26

相關(guān)類(lèi)別: 一抗

儲(chǔ)     存: 冷凍(-20℃)

宿     主: Rabbit

抗     原: KIAA0556

反應(yīng)種屬: Human, Mouse

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia.

Applications:

ELISA, IHC

Name of antibody:

KIAA0556

Immunogen:

Synthetic peptide of human KIAA0556

Full name:

KIAA0556

Synonyms:

JBTS26

SwissProt:

O60303

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200