兔抗KLF17多克隆抗體

Background:

Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Applications:

ELISA, IHC

Name of antibody:

KLF17

Immunogen:

Fusion protein of human KLF17

Full name:

Kruppel-like factor 17

Synonyms：

ZNF393; Zfp393; RP4-675G8.1

SwissProt:

Q5JT82

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human thyroid cancer

IHC Recommend dilution:

25-100