小鼠抗PSMD5單克隆抗體

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

Applications:

WB

Name of antibody:

PSMD5

Immunogen:

Fusion protein of human PSMD5

Full name:

proteasome 26S subunit, non-ATPase 5

Synonyms:

S5B

SwissProt:

Q16401

WB Predicted band size:

56 KD

WB Positive control:

A431, Jurkat cell lysates

WB Recommended dilution:

500-2000