小鼠抗SAT2單克隆抗體

Background:

SSAT2 (spermidine/spermine N1-acetyltransferase family member 2), also known as diamine acetyltransferase 2, polyamine N-acetyltransferase 2 or thialysine N-epsilon-acetyltransferase, is a 170 amino acid protein that exists as a homodimer and belongs to the acetyltransferase family. Localizing to cytoplasm, SSAT2 is found in bone, cervix, ovary and pineal gland. SSAT2, which shares 46% amino acid identity to SSAT1, is expressed in many of the same tissues as SSAT1, however SSAT1 is more widely expressed. SSAT2 contains one N-acetyltransferase domain and functions as an enzyme, catalyzing the acetylation of polyamines, and may also act as a transciptional co-activator. SSAT2 promotes ubiquitination of HIF-1alpha by stabilizing the interaction of Elongin C and VHL. The gene encoding SSAT 2 maps to human chromosome 17p13.1.

Applications:

WB, IF, FC

Name of antibody:

SAT2

Immunogen:

Fusion protein of human SAT2

Full name:

spermidine/spermine N1-acetyltransferase family member 2 (SAT2)

Synonyms:

SSAT2

SwissProt:

Q96F10

WB Predicted band size:

19 kDa

WB Positive control:

HepG2, Hela, SVT2, COS7 cell lysates

WB Recommended dilution:

200-1000