小鼠抗SIRT2單克隆抗體

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Applications:

WB, IF

Name of antibody:

SIRT2

Immunogen:

Fusion protein of human SIRT2

Full name:

sirtuin 2

Synonyms:

SIR2; SIR2L; SIR2L2

SwissProt:

Q8IXJ6

WB Predicted band size:

43 kDa

WB Positive control:

PC-12 cell, Rat Brain tissue and Mouse Brain tissue lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

25-50