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    • 品牌 : 通蔚生物
    • 目錄號 : TW12165
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
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中文名稱： 小鼠抗STAU1單克隆抗體

英文名稱： Anti-STAU1 mouse monoclonal antibody

別     名： staufen double-stranded RNA binding protein 1; STAU; PPP1R150

相關(guān)類別： 一抗

儲(chǔ)     存： 冷凍（-20℃）

宿     主： Mouse

抗     原： STAU1

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類型： mouse monoclonal

技術(shù)規(guī)格

Background:

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.

Applications:

WB

Name of antibody:

STAU1

Immunogen:

Fusion protein of human STAU1

Full name:

staufen double-stranded RNA binding protein 1

Synonyms:

STAU; PPP1R150

SwissProt:

O95793

WB Predicted band size:

63 KD

WB Positive control:

Jurkat, K562, HepG2, Hela cell lysates

WB Recommended dilution:

500-2000