兔抗AK2多克隆抗體

Background:

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.

Applications:

ELISA, WB, IHC

Name of antibody:

AK2

Immunogen:

Fusion protein of human AK2

Full name:

adenylate kinase 2

Synonyms：

ADK2; AK 2

SwissProt:

P54819

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human colon cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

26 kDa

WB Positive control:

Human placenta tissue and A549 cells, mouse brain tissue and hepG2 cells, Raji cells and human fetal liver tissue, hela cells

WB Recommended dilution:

500-2000