購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗COL11A2多克隆抗體
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Background: |
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. |
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Applications: |
IHC |
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Name of antibody: |
COL11A2 |
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Immunogen: |
Synthesized peptide derived from internal of human Collagen XI α2. |
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Full name: |
collagen, type XI, alpha 2 |
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Synonyms： |
HKE5; PARP; STL3; FBCG2; DFNA13; DFNB53 |
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SwissProt: |
P13942 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
