中文名稱(chēng): ARMC10抗原(重組蛋白)
概 述
Full name: |
armadillo repeat containing 10 |
Synonyms: |
SVH; PNAS112; PNAS-112; PSEC0198 |
Swissprot: |
Q8N2F6 |
Gene Accession: |
BC003586 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. |