兔抗CYP3A5多克隆抗體

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CYP3A5

Immunogen:

Synthetic peptide corresponding to a region derived from 238-250 amino acids of human CYP3A5

Full name:

cytochrome P450 family 3 subfamily A member 5

Synonyms:

CP35; PCN3; CYPIIIA5; P450PCN3

SwissProt:

P20815

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human liver cancer;Human prostate cancer

IHC Recommended dilution:

20-100