兔抗CYP17A1多克隆抗體

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Applications:

ELISA, IHC

Name of antibody:

CYP17A1

Immunogen:

Fusion protein of human CYP17A1

Full name:

cytochrome P450, family 17, subfamily A, polypeptide 1

Synonyms：

CPT7; CYP17; S17AH; P450C17

SwissProt:

P05093

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human gastric cancer

IHC Recommend dilution:

50-200