兔抗DAAM1多克隆抗體

Background:

Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.

Applications:

ELISA, WB, IHC

Name of antibody:

DAAM1

Immunogen:

Synthetic peptide of human DAAM1

Full name:

dishevelled associated activator of morphogenesis 1

SwissProt:

Q9Y4D1

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

123 kDa

WB Positive control:

Hela and 293T cells

WB Recommended dilution:

200-1000