中文名稱:ASAH2抗原(重組蛋白)
英文名稱: ASAH2 Antigen (Recombinant Protein)
別 名: HNAC1; BCDase; LCDase; NCDase; N-CDase
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ASAH2 |
技術(shù)規(guī)格:
Full name: |
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 |
Synonyms: |
HNAC1; BCDase; LCDase; NCDase; N-CDase |
Swissprot: |
Q9NR71 |
Gene Accession: |
BC107105 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. |