中文名稱:ATG4C抗原(重組蛋白)
英文名稱: ATG4C Antigen (Recombinant Protein)
別 名: APG4C; AUTL1; AUTL3; APG4-C
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ATG4C |
Full name: |
autophagy related 4C, cysteine peptidase |
Synonyms: |
APG4C; AUTL1; AUTL3; APG4-C |
Swissprot: |
Q96DT6 |
Gene Accession: |
BC033024 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. |