ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

BMI1抗原（重組蛋白）

規(guī)格：

數(shù)量：

購買數(shù)量

價(jià)格：￥

中文名稱：BMI1抗原（重組蛋白）

英文名稱： BMI1 Antigen (Recombinant Protein)

別名： PCGF4; RNF51; FLVI2/BMI1

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to N terminal 250 amino acids of human BMI1

技術(shù)規(guī)格：

Full name:	BMI1 polycomb ring finger oncogene
Synonyms:	PCGF4; RNF51; FLVI2/BMI1
Swissprot:	P35226
Gene Accession:	BC011652
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

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