中文名稱(chēng): 兔抗MAP2K4多克隆抗體
英文名稱(chēng): Anti-MAP2K4 rabbit polyclonal antibody
別 名: JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: MAP2K4
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background:
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Applications:
WB
Name of antibody:
MAP2K4
Immunogen:
Synthetic peptide of human MAP2K4
Full name:
mitogen-activated protein kinase kinase 4
Synonyms:
JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
SwissProt:
P45985
WB Predicted band size:
44 kDa
WB Positive control:
HUVEC cells
WB Recommended dilution:
500-1000