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  • PSMD8抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17105
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：40
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中文名稱： PSMD8抗原（重組蛋白）

英文名稱： PSMD8 Antigen (Recombinant Protein)

別       名： S14, p31, HIP6, HYPF, Nin1p, Rpn12

儲(chǔ)       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 94-350 amino acids of human PSMD8

技術(shù)規(guī)格

Full name:

proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Synonyms:

S14, p31, HIP6, HYPF, Nin1p, Rpn12

Swissprot:

P48556

Gene Accession:

BC001164

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.