中文名稱: FAIM2抗原(重組蛋白)
英文名稱: FAIM2 Antigen (Recombinant Protein)
別 名: LFG; LFG2; NGP35; NMP35; TMBIM2
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to N terminal 105 amino acids of human FAIM2 |
Full name: |
Fas apoptotic inhibitory molecule 2 |
Synonyms: |
LFG; LFG2; NGP35; NMP35; TMBIM2 |
Swissprot: |
Q9BWQ8 |
Gene Accession: |
BC000051 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. |