中文名稱: GGCX抗原(重組蛋白)
英文名稱: GGCX Antigen (Recombinant Protein)
別 名: VKCFD1
儲 存:冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human GGCX |
Full name: |
gamma-glutamyl carboxylase |
Synonyms: |
VKCFD1 |
Swissprot: |
P38435 |
Gene Accession: |
NP_000812 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. |