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  • METTL7A抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17385
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱： METTL7A 抗原（重組蛋白）

英文名稱： METTL7A Antigen (Recombinant Protein)

別       名： methyltransferase like 7A; AAM-B

相關(guān)類別： 抗原

儲    存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 30-244 amino acids of human METTL7A

技術(shù)規(guī)格

Full name:

methyltransferase like 7A

Synonyms:

AAM-B

Swissprot:

Q9H8H3

Gene Accession:

BC004492

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.