中文名稱: SUV39H1抗原(重組蛋白)
英文名稱: SUV39H1 Antigen (Recombinant Protein)
別 名: MG44; KMT1A; SUV39H; H3-K9-HMTase 1
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 243-396 amino acids of human SUV39H1 |
Full name: |
suppressor of variegation 3-9 homolog 1 |
Synonyms: |
MG44; KMT1A; SUV39H; H3-K9-HMTase 1 |
Swissprot: |
O43463 |
Gene Accession: |
BC006238 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. |