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  • SMAD5抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17738
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：75
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中文名稱：SMAD5抗原（重組蛋白）

英文名稱： SMAD5 Antigen (Recombinant Protein)

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from C terminal 300 amino acids of human SMAD5


技術(shù)規(guī)格

Full name:

SMAD family member 5

Synonyms:

DWFC; JV5-1; MADH5

Swissprot:

Q99717

Gene Accession:

BC009682

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by BMP type 1 receptor kinase. Three transcript variants encoding the same protein have been found for this gene. Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1.