兔抗TUBGCP4多克隆抗體

Background:

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

TUBGCP4

Immunogen:

Fusion protein of human TUBGCP4

Full name:

tubulin gamma complex associated protein 4

Synonyms:

76P; GCP4; GCP-4; Grip76; MCCRP3

SwissProt:

Q9UGJ1

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

76 kDa

WB Positive control:

HT-29, NIH/3T3, 231, Hela, RAW264.7, K562 and LOVO cell lysates

WB Recommended dilution:

500-2000