中文名稱:RIC3抗原(重組蛋白)
英文名稱: RIC3 Antigen (Recombinant Protein)
別 名: AYST720; PRO1385
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 170-369 amino acids of human RIC3 |
Full name: |
RIC3 acetylcholine receptor chaperone |
Synonyms: |
AYST720; PRO1385 |
Swissprot: |
Q7Z5B4 |
Gene Accession: |
BC022455 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. |