中文名稱:GATM抗原(重組蛋白)
英文名稱: GATM Antigen (Recombinant Protein)
別 名: AT; AGAT; CCDS3
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 224-423 amino acids of human GATM |
Full name: |
glycine amidinotransferase |
Synonyms: |
AT; AGAT; CCDS3 |
Swissprot: |
P50440 |
Gene Accession: |
BC004141 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders. |