兔抗EGFR(Phospho-Tyr1016) 多克隆抗體

Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Applications:

WB

Name of antibody:

EGFR(Phospho-Tyr1016)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 1016 (D-E-Y(p)-L-I) derived from Human EGFR.

Full name:

epidermal growth factor receptor

Synonyms：

ERBB; HER1; mENA; ERBB1; PIG61

SwissProt:

P00533

WB Predicted band size:

134 kDa

WB Positive control:

Hela cells lysates

WB Recommended dilution:

500-1000