兔抗MRPL24多克隆抗體

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein.

Applications:

WB, IHC

Name of antibody:

MRPL24

Immunogen:

Synthesized peptide derived from internal of human MRPL24.

Full name:

mitochondrial ribosomal protein L24

Synonyms：

L24mt; MRP-L18; MRP-L24

SwissProt:

Q96A35

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

25 kDa

WB Positive control:

Huvec cells lysate

WB Recommended dilution:

500-3000