兔抗QARS1多克隆抗體

Background:

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Applications:

ELISA, IHC

Name of antibody:

QARS1

Immunogen:

Fusion protein of human QARS1

Full name:

glutaminyl-tRNA synthetase 1

Synonyms:

QARS; GLNRS; MSCCA; PRO2195

SwissProt:

P47897

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

20-100