兔抗ENPP1多克隆抗體

Background:

This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Applications:

ELISA, IHC

Name of antibody:

ENPP1

Immunogen:

Synthetic peptide of human ENPP1

Full name:

ectonucleotide pyrophosphatase/phosphodiesterase 1

Synonyms：

M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1

SwissProt:

P22413

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human ovarian cancer and Human thyroid cancer

IHC Recommend dilution:

10-50