兔抗RASGRF1多克隆抗體

Background:

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit.

Applications:

IHC

Name of antibody:

RASGRF1

Immunogen:

Synthesized peptide derived from Internal of human Ras-GRF1.

Full name:

Ras protein-specific guanine nucleotide-releasing factor 1

Synonyms：

GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1

SwissProt:

Q13972

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100