兔抗ERBB4(Phospho-Tyr1284) 多克隆抗體

Background:

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.

Applications:

WB

Name of antibody:

ERBB4(Phospho-Tyr1284)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine 1284 (P-E-Y(p)-L-S) derived from Human HER4

Full name:

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Synonyms：

HER4; ALS19; p180erbB4

SwissProt:

Q15303

WB Predicted band size:

147 kDa

WB Positive control:

Huvec cells lysates treated with EGF

WB Recommended dilution:

500-1000