兔抗ESR1多克隆抗體

Background:

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Applications:

ELISA, IHC

Name of antibody:

ESR1

Immunogen:

Synthetic peptide of human ESR1

Full name:

estrogen receptor 1

Synonyms：

ER, ESR, Era, ESRA, NR3A1

SwissProt:

P03372

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human brain and Human thyroid cancer

IHC Recommend dilution:

100-300