兔抗FBXL4多克隆抗體

Background:

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

FBXL4

Immunogen:

Synthetic peptide of human FBXL4

Full name:

F-box and leucine rich repeat protein 4

Synonyms:

FBL4; FBL5; MTDPS13

SwissProt:

Q9UKA2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and Human lung cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

70 kDa

WB Positive control:

LOVO cell lysate

WB Recommended dilution:

200-1000