兔抗FBXW7多克隆抗體

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.

Applications:

ELISA, IHC

Name of antibody:

FBXW7

Immunogen:

Fusion protein of human FBXW7

Full name:

F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

Synonyms：

AGO; CDC4; FBW6; FBW7; hAgo; FBX30; FBXW6; SEL10; hCdc4; FBXO30; SEL-10

SwissProt:

Q969H0

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and human thyroid cancer

IHC Recommend dilution:

100-300