兔抗FGB多克隆抗體

Background:

The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Applications:

WB

Name of antibody:

FGB

Immunogen:

Fusion protein of human FGB

Full name:

fibrinogen beta chain

Synonyms：

MGC104327; MGC120405; FGB

SwissProt:

P02675

WB Predicted band size:

56 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

500-2000