兔抗FGFR2多克隆抗體

Background:

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform.

Applications:

ELISA, IHC

Name of antibody:

FGFR2

Immunogen:

Synthetic peptide of human FGFR2

Full name:

Fibroblast growth factor receptor 2

Synonyms：

BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM

SwissProt:

P21802

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human brain

IHC Recommend dilution:

25-100