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      • 兔抗NANOS2多克隆抗體

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        • 品牌 : 通蔚生物
        • 目錄號(hào) : TW20484
        • 應(yīng)用 : 僅供科研使用
        • 保存條件 : 低溫保存
        • 貨期 : 現(xiàn)貨
        • 商品庫(kù)存:80
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      中文名稱(chēng):  兔抗NANOS2多克隆抗體


      英文名稱(chēng):  Anti-NANOS2 rabbit polyclonal antibody


      別      名:  NOS2


      相關(guān)類(lèi)別:  一抗


      儲(chǔ)      存:  冷凍(-20℃)


      宿      主:  Rabbit


      抗     原:  NANOS2


      反應(yīng)種屬:  Human


      標(biāo)  記  物:  Unconjugate


      克隆類(lèi)型:  rabbit polyclonal


      技術(shù)規(guī)格

      Background:

      Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state (By similarity).

      Applications:

      ELISA, IHC

      Name of antibody:

      NANOS2

      Immunogen:

      Fusion protein of human NANOS2

      Full name:

      nanos C2HC-type zinc finger 2

      Synonyms:

      NOS2; ZC2HC12B

      SwissProt:

      P60321

      ELISA Recommended dilution:

      2000-5000

      IHC positive control:

      Human liver cancer and Human breast cancer

      IHC Recommend dilution:

      50-200