中文名稱: 兔抗NFASC多克隆抗體
英文名稱: Anti-NFASC rabbit polyclonal antibody
別 名: NF, NRCAML
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: NFASC
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. |
Applications: |
ELISA, IHC |
Name of antibody: |
NFASC |
Immunogen: |
Synthetic peptide of human NFASC |
Full name: |
neurofascin |
Synonyms: |
NF, NRCAML |
SwissProt: |
O94856 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
50-200 |