中文名稱:兔抗SETD2多克隆抗體
英文名稱: Anti-SETD2 rabbit polyclonal antibody
別 名: HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP
相關(guān)類別: 一抗
抗 原: SETD2
儲 存: 冷凍(-20℃)
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse
標(biāo)記物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Applications: |
ELISA, IHC |
Name of antibody: |
SETD2 |
Immunogen: |
Fusion protein of human SETD2 |
Full name: |
SET domain containing 2 |
Synonyms: |
HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP |
SwissProt: |
Q9BYW2 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human tonsil and human cervical cancer |
IHC Recommend dilution: |
50-200 |