兔抗PAFAH1B1多克隆抗體

Background:

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Applications:

ELISA, IHC

Name of antibody:

PAFAH1B1

Immunogen:

Synthetic peptide of human PAFAH1B1

Full name:

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)

Synonyms：

MDS, LIS1, LIS2, MDCR, PAFAH

SwissProt:

P43034

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human ovarian cancer and Human brain

IHC Recommend dilution:

25-100