兔抗SIGLEC5多克隆抗體

Background:

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Applications:

ELISA, IHC

Name of antibody:

SIGLEC5

Immunogen:

Fusion protein of human SIGLEC5

Full name:

sialic acid binding Ig-like lectin 5

Synonyms：

CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5

SwissProt:

O15389

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

25-100