兔抗GLI3多克隆抗體

Background:

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

Applications:

ELISA, WB, IHC

Name of antibody:

GLI3

Immunogen:

Synthetic peptide of human GLI3

Full name:

GLI family zinc finger 3

Synonyms：

PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190

SwissProt:

P10071

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

170 kDa

WB Positive control:

Mouse liver tissue

WB Recommended dilution:

200-1000