兔抗GLYR1多克隆抗體

Background:

Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation (PubMed:29759984). Facilitates Pol II transcription through nucleosomes (PubMed:29759984). Binds DNA (in vitro) (PubMed:29759984). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Promotes KDM1B demethylase activity (PubMed:23260659). Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (PubMed:29759984). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). Putative oxidoreductase (PubMed:23260659).

Applications:

ELISA, WB

Name of antibody:

GLYR1

Immunogen:

Synthetic peptide of human GLYR1

Full name:

glyoxylate reductase 1 homolog

Synonyms:

NP60; BM045; HIBDL; N-PAC

SwissProt:

Q49A26

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

61 kDa

WB Positive control:

Hela, Jurkat, K562 and HUVEC cells

WB Recommended dilution:

500-2000