兔抗GPR153多克隆抗體

Background:

This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells.

Applications:

ELISA, IHC

Name of antibody:

GPR153

Immunogen:

Synthetic peptide of human GPR153

Full name:

G protein-coupled receptor 153

Synonyms:

PGR1

SwissProt:

Q6NV75

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

30-150