兔抗PPP4C多克隆抗體

Background:

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Applications:

WB

Name of antibody:

PPP4C

Immunogen:

Fusion protein of human PPP4C

Full name:

protein phosphatase 4, catalytic subunit

Synonyms：

PP4; PPX; PP4C; PPH3; PPP4

SwissProt:

P60510

WB Predicted band size:

35 kDa

WB Positive control:

293T, NIH/3T3, MCF-7 and HO-8910 cells, mouse testis and spleen tissue

WB Recommended dilution:

500-2000