兔抗PTH1R多克隆抗體

Background:

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

PTH1R

Immunogen:

Fusion protein of human PTH1R

Full name:

parathyroid hormone 1 receptor

Synonyms:

PFE; PTHR; PTHR1

SwissProt:

Q03431

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human esophagus cancer

IHC Recommend dilution:

50-300