兔抗GRK2多克隆抗體

Background:

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

Applications:

ELISA, IHC

Name of antibody:

GRK2

Immunogen:

Synthetic peptide of human GRK2

Full name:

G protein-coupled receptor kinase 2

Synonyms:

BARK1; ADRBK1; BETA-ARK1

SwissProt:

P25098

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

100-300