ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫(kù)

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

兔抗GSDMA多克隆抗體

規(guī)格：

數(shù)量：

購(gòu)買(mǎi)數(shù)量

價(jià)格：￥

品牌 : 通蔚生物
目錄號(hào) : TW22193
應(yīng)用 : 僅供科研使用
保存條件 : 低溫保存
貨期 : 現(xiàn)貨
商品庫(kù)存：75

中文名稱：兔抗GSDMA多克隆抗體

英文名稱： Anti-GSDMA rabbit polyclonal antibody

別名： gasdermin A; GSDM; FKSG9; GSDM1

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： GSDMA

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).

Applications:

ELISA, WB, IHC

Name of antibody:

GSDMA

Immunogen:

Fusion protein of human GSDMA

Full name:

gasdermin A

Synonyms:

GSDM; FKSG9; GSDM1

SwissProt:

Q96QA5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human ovarian cancer

IHC Recommend dilution:

100-200

WB Predicted band size:

49 kDa

WB Positive control:

LO2 and 293T cell lysates

WB Recommended dilution:

500-2000

021-54845833/15800441009