購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
STAP1 |
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Immunogen: |
Fusion protein of human STAP1 |
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Full name: |
signal transducing adaptor family member 1 |
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Synonyms: |
BRDG1; STAP-1 |
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SwissProt: |
Q9ULZ2 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
